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Moving Forward After GLP-1s: Your Guide to Weight Management and Healthy Living

Medications like semaglutide (Wegovy) and tirzepatide (Zepbound) have been game-changers for many people looking to lose weight. They work wonders by helping you feel fuller, longer. But what happens when you stop taking them, or if they become too expensive to continue? It's a common concern, and it's definitely possible to maintain your health journey even after or without these medications.



Understanding the Journey After GLP-1s


First things first, if you've stopped taking a GLP-1 medication, or are considering it due to cost, know that it's completely normal to wonder about what comes next. One thing many people experience is some weight regain. This isn't a personal failure, it's often just how our bodies are wired. GLP-1s are powerful tools, and when you take them away, your body's natural appetite and metabolic processes can readjust.


Think of it like this: GLP-1s were giving your body a helpful nudge in a certain direction. Now, it's time to actively steer the ship yourself! The good news is, you absolutely can maintain your weight loss progress and continue to live a healthy life using other effective strategies.


Your Toolkit for Weight Management and Maintenance (Without GLP-1s)


The key to long-term success after or without GLP-1s lies in building a sustainable, healthy lifestyle. This involves a few core areas:


  • Nutrition: Fueling Your Body the Right Way

    • Focus on Whole Foods:  This means prioritizing fruits, vegetables, lean proteins (like chicken, fish, beans, lentils), and whole grains (like brown rice, quinoa, oats). These foods are packed with nutrients and fiber, which help you feel full and satisfied.

    • Portion Control:  Become mindful of your portion sizes. Using smaller plates, measuring out servings, and paying attention to your body's hunger and fullness cues can make a big difference. Try eating slowly and savoring your meals.

    • Limit Processed Foods, Sugary Drinks, Alcohol and Unhealthy Fats: These can be sneaky sources of extra calories and can work against your weight management goals. Think about swapping sugary sodas for water, choosing whole fruits over sugary snacks, and cooking at home more often to control ingredients.

    • Meal Planning and Prepping:  Taking a little time each week to plan your meals and prepare some ingredients can be a game-changer. It makes healthy eating much easier and helps you avoid impulsive, less healthy choices when you're hungry.


  • Physical Activity: Getting Your Body Moving

    • Regular Exercise is Key: Aim for a mix of both cardiovascular exercise (like brisk walking, jogging, swimming, dancing) and strength training (using weights or resistance bands). Cardio helps burn calories, while strength training builds muscle mass, which boosts your metabolism over time.

    • Find Activities You Enjoy:  Exercise doesn't have to be a chore! Experiment with different activities until you find something you genuinely like. It could be hiking, cycling, yoga, Zumba, or even just walking your dog. The more you enjoy it, the more likely you are to stick with it.

    • Start Gradually and Be Consistent:  If you're not used to exercising regularly, start slowly and gradually increase the intensity and duration. Consistency is more important than intensity, especially in the beginning. Even 30 minutes of moderate activity most days of the week can make a significant difference.


  • Lifestyle Factors Beyond Diet and Exercise: The Big Picture

    • Prioritize Sleep:  Getting enough quality sleep (aim for 7-9 hours for most adults) is crucial for weight management. Sleep deprivation can disrupt hormones that regulate appetite, leading to increased hunger and cravings.

    • Manage Stress:  Chronic stress can also impact your weight. Find healthy ways to manage stress, such as mindfulness, meditation, spending time in nature, pursuing hobbies, or talking to a therapist if needed.

    • Stay Hydrated:  Drinking plenty of water throughout the day is important for overall health and can also help you feel fuller and potentially reduce snacking.


What About Other Weight Management Medications?


While GLP-1s are highly effective, they aren't the only option. There are other types of weight management medications available that work through different mechanisms. For more details, see my blog post Beyond Diet and Exercise: Exploring FDA-Approved Weight Loss Medications. However, it is absolutely essential to discuss these options with your doctor.  They can assess your individual health profile, medical history, and weight management goals to determine if another medication might be appropriate and safe for you. Never start a new medication without consulting your healthcare provider.


Long-Term Success and Mindset


Weight management is a marathon, not a sprint. It's about building sustainable habits and making healthy choices a part of your everyday life. Here are a few things to keep in mind for long-term success:


  • Focus on Lifestyle Changes, Not Quick Fixes: Fad diets and extreme measures are rarely sustainable and can often lead to rebound weight gain. Focus on making gradual, realistic changes that you can maintain over time.

  • Set Realistic Goals:  Aim for gradual and steady weight loss, if that's your goal. Even losing a small amount of weight (5-10% of your body weight) can have significant health benefits.

  • Celebrate Small Victories:  Acknowledge and celebrate your progress along the way, no matter how small. This helps you stay motivated and positive.

  • Be Kind to Yourself:  Everyone has ups and downs. If you have a setback, don't get discouraged. Just get back on track with your healthy habits.

  • Seek Support:  Having a support system can be incredibly helpful. Talk to your friends and family, consider joining a support group, or work with a registered dietitian or certified personal trainer for professional guidance.


Moving Forward with Confidence


Managing your weight after stopping GLP-1 medications, or without ever using them, is definitely achievable. By focusing on a balanced approach that includes healthy eating, regular physical activity, and mindful lifestyle habits, you can continue on your journey towards better health and well-being. Remember to be patient with yourself, celebrate your progress, and always consult with your healthcare provider for personalized advice and support. You've got this!


If you'd like to discuss your personal situation and receive individualized advice, schedule an appointment with the Institute for Diabetes, Endocrinology, Adiposity, and Longevity today.


Till next time,

Dr. Koren


DISCLAIMER: The content on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have read or watched on this website. The mention of any product, treatment, or organization on this website does not indicate the author's endorsement. The product names referenced here are trademarks owned by their respective manufacturers. The author disclaims any legal liability for personal injury or any other damage or loss resulting directly or indirectly from the use or misuse of this website's contents.

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